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N~3~-[3-(5-methoxypyridin-3-yl)benzyl]pyridine-2,3-diamine

Development stage
Unknown
Modality
Small Molecules
01

Overview

N~3~-[3-(5-methoxypyridin–​³–​YL)benzyl]pyridine–​²,³–​diamine is an experimental small molecule compound belonging to the phenylpyridines class. It has a molecular formula of C₁₈H₁₈N₄O and a molecular weight of approximately 306.36 Da[1][7][8]. The compound is not approved for clinical use in any country and has no known marketed indications or completed clinical trials[1]. It is referenced in chemical and structural databases but lacks detailed published information on its mechanism of action or therapeutic applications. However, it has been associated with β-secretase 1 (BACE1), suggesting potential research interest as a BACE1 inhibitor—a target relevant to Alzheimer's disease drug discovery efforts[5].

Other names
2,3-pyridinediamine, N~3~-[[3-(5-methoxy-3-pyridinyl)phenyl]methyl]N~3~-[3-(5-methoxy-3-pyridinyl)benzyl]-2,3-pyridinediamine3-N-{[3-(5-methoxypyridin-3-yl)phenyl]methyl}pyridine-2,3-diamineN'-[[3-(5-methoxypyridin-3‑yl)phenyl]methyl]pyridine‑2,​ ³‑diamine
02

Targets

BACE1 (Beta-site APP-cleaving enzyme 1)

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